What Antibiotics Cover Anaerobes

Infections caused by gram negative bacteria such as escherichia coli and klebsiella particularly pseudomonas aeruginosa effective against aerobic bacteria not obligate facultative anaerobes and tularemia all aminoglycosides are ineffective when taken orally. In summary the antibiotics studied have predominantly been broad spectrum covering both gram positive and gram negative bacteria with the exception of penicillin and clindamycin that have relatively poor gram negative activity 23 inclusion of anaerobic cover was not universal with only the following antibiotics having anti anaerobic.

Antibiotics For Anaerobic Infections Antibiotics Lecture 6

Facultatively anaerobic bacteria can grow in the presence or absence of air.

What antibiotics cover anaerobes. Microaerophilic bacteria do not grow at all aerobically or grow poorly but grow better under 10 carbon dioxide or anaerobically. Metronidazole flagyl po and iv mechanism. Obligately anaerobic bacteria do not grow on solid media in room air 0 04 carbon dioxide and 21 oxygen.

Anaerobic infections are caused by anaerobic bacteria. Oropharyngeal anaerobic infections and lung abscesses oropharyngeal anaerobic infections may not respond to penicillin and thus require a drug effective against penicillin resistant anaerobes see below. With allergies to pcn who can t take pip tazo 3 imipenem or meropenem or doripenem.

It is a prescription drug prescribed for individuals suffering from abscesses in the abdomen liver pelvis or brain formed by anaerobic bacteria. Options for covering both pseudomonas and anaerobes. Apart from these drugs all antibiotics listed below have excellent bacteroides coverage and as a general rule do not need to double cover anaerobes.

Selectively taken up by anaerobic bacteria and reduced by proteins in the electron transport chain leading to dna disruption. The anaerobic gram positive cocci and anaerobic gram positive non sporeforming rods such as anaerobic bacteria bifidobacterium eubacterium lactobacillus and propionibacterium species are for the most part components of the normal flora of the mucosal surfaces and to a lesser extent the skin. 1 pip tazo zosyn or 2 aztreonam metronizadole or this is on drmc s guidelines recommend this combination in pts.

The drug is also used to treat other types of infection such as giardia infections and. The history of anaerobes the composition of normal flora in humans and the pathophysiology clinical clues and recovery of these organisms are also discussed separately. One of the antibiotics for anaerobic bacterial infection is metronidazole which is the generic name of flagyl.

Microbiology anaerobic gram positive non sporeforming rods and anaerobic gram positive cocci. Antibiotics that cover the difficult to kill gram positive bacteria. Combinations of antibiotics are therefore needed to cover the gut flora such as teicoplanin or vancomycin which only have gram positive activity plus metronidazole which only covers anaerobes plus either ciprofloxacin or gentamicin both of which have excellent gran negative activity.

Antibiotics are chosen based on infection site and thus likely organisms. History and role in normal human flora and pathophysiology clinical clues and recovery of organisms in anaerobic infections. Antibiotics by class generic name brand names common uses possible side effects mechanism of action aminoglycosides.

Surgical Infections A Microbiological Study