What Is The Difference Between Statistical Significance And Clinical Significance

In evidence based research practice statistical significance must always be determined before determination of clinical significance. Clinical significance is a measure of whether a research result matters in the real world.

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It s also known as clinical importance and this might be a helpful way to remember the difference between clinical.

What is the difference between statistical significance and clinical significance. I can use clinical significance to support positive outcomes in my project outcome by ensuring that the result is statistically significant. When we find a difference where p 0 05 we call this statistically significant. Clinical significance is a subjective interpretation of a research result as practical or meaningful for the patient and thus likely to affect provider behavior.

This difference was not statistically significant 8. However if the researchers were to look at the results from an application standpoint their conclusion may have been different. This is due to the fact that majority of statistically significant findings are normally have.

Statistical significance indicates the presence of a relationship between two events that is not a result of chance. So in simple terms if a treatment makes a positive and noticeable improvement toâ a patient we can call thisâ clinically significant or clinically important. However clinical significance indicates the level of importance from the clinical point of view of this relationship.

Clinical significance is a little bit different than statistical significance. However clinical significance is usually a subjective evaluation and cannot be established by a single experiential test. In contrast statistical significance is ruled by the p value and confidence intervals.

Statistical significance has to do with the likelihood that a research result is true i e a real effect of the intervention and not merely a matter of chance.

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