What Is The Function Of Dextran
Iron is important for many functions in the body especially for the transport of oxygen in the blood. Dextran is soluble in water and organic solvents and this feature can be used in the preparation of different structures through blending dextran with bioactive agents or hydrophobic polymers.
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Iron dextran may also be used for purposes not listed in this medication guide.
What is the function of dextran. Iron dextran is used to treat iron deficiencies and iron deficiency anemia low red blood cells. Dextran is a biodegradable neutral bacterial exopolysaccharide consisting of repeating glucose subunits. Dextran c18h32o16 cid 4125253 structure chemical names physical and chemical properties classification patents literature biological activities safety hazards toxicity information supplier lists and more.
Dextran is used in the osmotic stress technique for applying osmotic pressure to biological molecules. Used in isotonic sodium chloride solution to treat shock and to relieve edema of nephrosis. Heparin and dextran are polyanions which form insoluble salts with the cationic histones.
High molecular weight dextran is a plasma volume expander made from natural sources of sugar glucose. Medical dictionary for the dental professions farlex 2012. Dextran has been used in immobilization in biosensors.
The branches are mostly 1 2 glucose units long. Severe blood loss can decrease oxygen levels and can lead to organ failure brain damage coma and possibly death. Get the latest public health information from cdc.
Dextran is an α d 1 6 glucose linked glucan with side chains 1 3 linked to the backbone units of the dextran biopolymer. Dextran has also been used in bead form to aid in bioreactor applications. It is also used in some size exclusion chromatography matrices.
Dextran is a polymer of glucose. Historically dextrans had been long recognized as contaminants in sugar processing and other food production. Deks tran any of several water soluble high molecular weight glucose polymers.
Iron dextran is a form of the mineral iron. In dextran sulphate it is derivatised with sulphonate groups creating a polyanionic material immobilised heparin is sometimes used as an affinity matrix for purification of dna binding proteins like transcription factors. The degree of branching is approximately 5 in native unfractionated dextran and decreases with decreasing molecular weight.
An example is sephadex. Covid 19 is an emerging rapidly evolving situation. Infed iron dextran injection usp is a dark brown slightly viscous sterile liquid complex of ferric hydroxide and dextran for intravenous or intramuscular use.
It works by restoring blood plasma lost through severe bleeding. Each ml contains the equivalent of 50 mg of elemental iron as an iron dextran complex approximately 0 9 sodium chloride in water for injection.
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